Discovery of novel microRNAs in female reproductive tract using next generation sequencing.

MicroRNAs (miRNAs) are small non-coding RNAs that mediate post-transcriptional gene silencing. Over 700 human miRNAs have currently been identified, many of which are mutated or de-regulated in diseases. Here we report the identification of novel miRNAs through deep sequencing the small RNAome (<...

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Bibliographic Details
Main Authors: Chad J Creighton, Ashley L Benham, Huifeng Zhu, Mahjabeen F Khan, Jeffrey G Reid, Ankur K Nagaraja, Michael D Fountain, Olivia Dziadek, Derek Han, Lang Ma, Jong Kim, Shannon M Hawkins, Matthew L Anderson, Martin M Matzuk, Preethi H Gunaratne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2835764?pdf=render