Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In this study, we show that Tcf7l1a is one such transcription factor that acts cell-autonomously to specify the eye field in zebrafish. Despite the much-reduced eye field in tcf7...

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Bibliographic Details
Main Authors: Rodrigo M Young, Thomas A Hawkins, Florencia Cavodeassi, Heather L Stickney, Quenten Schwarz, Lisa M Lawrence, Claudia Wierzbicki, Bowie YL Cheng, Jingyuan Luo, Elizabeth Mayela Ambrosio, Allison Klosner, Ian M Sealy, Jasmine Rowell, Chintan A Trivedi, Isaac H Bianco, Miguel L Allende, Elisabeth M Busch-Nentwich, Gaia Gestri, Stephen W Wilson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
eye
development
genetics
tcf7l1
zebrafish
Online Access:https://elifesciences.org/articles/40093

Internet

https://elifesciences.org/articles/40093

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