An Adaptive Control Scheme for Interleukin-2 Therapy

Summary: Regulatory T cells (Treg) are suppressor cells that control self-reactive and excessive effector conventional T helper cell (Tconv) responses. Breakdown of the balance between Tregs and Tconvs is a hallmark of autoimmune and inflammatory diseases. Interleukin-2 (IL-2) is a growth factor for...

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Bibliographic Details
Main Authors: Sahamoddin Khailaie, Ghazal Montaseri, Michael Meyer-Hermann
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220308555