sim1000G: a user-friendly genetic variant simulator in R for unrelated individuals and family-based designs

Abstract Background Simulation of genetic variants data is frequently required for the evaluation of statistical methods in the fields of human and animal genetics. Although a number of high-quality genetic simulators have been developed, many of them require advanced knowledge in population genetic...

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Bibliographic Details
Main Authors: Apostolos Dimitromanolakis, Jingxiong Xu, Agnieszka Krol, Laurent Briollais
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Bioinformatics
Subjects:
NGS
Online Access:http://link.springer.com/article/10.1186/s12859-019-2611-1