Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

<p>Abstract</p> <p>Background</p> <p>The β-amyloid precursor protein (APP) and the related β-amyloid precursor-like proteins (APLPs) undergo complex proteolytic processing giving rise to several fragments. Whereas it is well established that Aβ accumulation is a central...

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Bibliographic Details
Main Authors: Eils Roland, Prinz Marco, Gretz Norbert, Tschäpe Jakob-Andreas, Filippov Mikhail A, Aydin Dorothee, Brors Benedikt, Müller Ulrike C
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/160