Comprehensive Proteomic Characterization of Ontogenic Changes in Hematopoietic Stem and Progenitor Cells

Hematopoietic stem and progenitor cells (HSPCs) in the fetus and adult possess distinct molecular landscapes that regulate cell fate and change their susceptibility to initiation and progression of hematopoietic malignancies. Here, we applied in-depth quantitative proteomics to comprehensively descr...

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Bibliographic Details
Main Authors: Maria Jassinskaja, Emil Johansson, Trine Ahn Kristiansen, Hugo Åkerstrand, Kristoffer Sjöholm, Simon Hauri, Johan Malmström, Joan Yuan, Jenny Hansson
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717317229