Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase

Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase

Inhibition of α-amylase and α-glucosidase by specified synthetic compounds during the digestion of starch helps control post-prandial hyperglycemia and could represent a potential therapy for type II diabetes mellitus. A new series of spiroheterocyclic compounds bearing oxindole/be...

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Bibliographic Details
Main Authors: Mezna Saleh Altowyan, Assem Barakat, Abdullah Mohammed Al-Majid, H.A. Al-Ghulikah
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
spiroindolone
antidiabetic
hypoglycemic
α-amylase
α-glucosidase
Online Access:https://www.mdpi.com/1420-3049/24/12/2342

Internet

https://www.mdpi.com/1420-3049/24/12/2342

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