Impact of the change in the antitubercular regimen from three to four drugs on cure and frequency of adverse reactions in tuberculosis patients from Brazil: A retrospective cohort study.

BACKGROUND:The Ministry of Health in Brazil included ethambutol in the intensive phase of sensible tuberculosis (TB) treatment in March 2010, due to the increasing drug resistance, and implemented the fixed dose combination in the TB treatment guidelines. METHODS:A retrospective cohort study was per...

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Bibliographic Details
Main Authors: María B Arriaga, Ninfa M C Torres, Nelia C N Araujo, Simone C C Caldas, Bruno B Andrade, Eduardo M Netto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227101