A defined subset of clonal retinal stem cell spheres is biased to RPE differentiation

Summary: Retinal stem cells (RSCs) are rare pigmented cells found in the pigmented ciliary layer of the mammalian retina. Studies show that RSCs can replicate to maintain the stem cell pool and produce retinal progenitors that differentiate into all retinal cell types. We classified RSCs based on th...

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Bibliographic Details
Main Authors: Tahani W. Baakdhah, Brenda Coles, Derek van der Kooy
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221005423