Comparison of Injuring Effects of Vesicant, Irritant, and Nonvesicant Anticancer Drugs on Endothelial Cells

Abstract.: Anticancer drugs are classified as vesicant, irritant, and nonvesicant drugs on the basis of frequency of their vascular disorder. In this study, we compared the injuring effects of three typical anticancer drugs of each class on porcine aorta endothelial cells (PAECs). The concentration...

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Bibliographic Details
Main Authors: Takaaki Yamada, Nobuaki Egashira, Maiko Imuta, Ayami Bando, Takahisa Yano, Mami Saito, Ryozo Oishi
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319306450