Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.

Glioblastoma Multiforme (GBM) is a malignant astrocytic tumor associated with low survival rates because of aggressive infiltration of tumor cells into the brain parenchyma. Expression of the actin binding protein alpha-actinin has been strongly correlated with the invasive phenotype of GBM in vivo....

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Bibliographic Details
Main Authors: Shamik Sen, Meimei Dong, Sanjay Kumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2793025?pdf=render