The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity

The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity

The nonenzymatic adduction of malondialdehyde (MDA) to the protein amino groups leads to the formation of malondialdehyde-lysine (MDALys). The degree of unsaturation of biological membranes and the intracellular oxidative conditions are the main factors that modulate MDALys formation. The low concen...

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Bibliographic Details
Main Authors: Mariona Jové, Natàlia Mota-Martorell, Irene Pradas, Meritxell Martín-Gari, Victoria Ayala, Reinald Pamplona
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
advanced lipoxidation end-products
aging
carbonyl-amine reaction
cytotoxicity
dietary restriction
longevity
Online Access:https://www.mdpi.com/2076-3921/9/11/1132

Internet

https://www.mdpi.com/2076-3921/9/11/1132

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