Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease

Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. However, its molecular pathogenesis is incompletely characterized and clinical biomarkers remain scarce. The aims of these experiments were to identify and characterize liver protein alterations...

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Main Authors: Christos Spanos, Elaina M. Maldonado, Ciarán P. Fisher, Petchpailin Leenutaphong, Ernesto Oviedo-Orta, David Windridge, Francisco J. Salguero, Alexandra Bermúdez-Fajardo, Mark E. Weeks, Caroline Evans, Bernard M. Corfe, Naila Rabbani, Paul J. Thornalley, Michael H. Miller, Huan Wang, John F. Dillon, Alberto Quaglia, Anil Dhawan, Emer Fitzpatrick, J. Bernadette Moore
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Proteome Science
Subjects:
Non-alcoholic fatty liver disease
Glyoxalase
Methylglyoxal
Proteomics
iTRAQ
Online Access:http://link.springer.com/article/10.1186/s12953-018-0131-y

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http://link.springer.com/article/10.1186/s12953-018-0131-y

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