c-Jun N-terminal Kinase as a Therapeutic Target in Experimental Autoimmune Encephalomyelitis

c-Jun N-terminal Kinase as a Therapeutic Target in Experimental Autoimmune Encephalomyelitis

c-Jun N-terminal kinase (JNK) is upregulated during multiple sclerosis relapses and at the peak of experimental autoimmune encephalomyelitis (EAE). We aim to investigate the effects of pharmacological pan-JNK inhibition on the course of myelin oligodendrocyte glycoprotein (MOG<sub>35-55</su...

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Bibliographic Details
Main Authors: Maud Bagnoud, Myriam Briner, Jana Remlinger, Ivo Meli, Sara Schuetz, Maximilian Pistor, Anke Salmen, Andrew Chan, Robert Hoepner
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
multiple sclerosis
immunotherapy
mitogen-activated protein kinases
MAPK
SP600125
neuroinflammation
Online Access:https://www.mdpi.com/2073-4409/9/10/2154

Internet

https://www.mdpi.com/2073-4409/9/10/2154

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