PGK1 as predictor of CXCR4 expression, bone marrow metastases and survival in neuroblastoma.

BACKGROUND AND AIM: A close relationship between phosphoglycerate kinase 1 (PGK1) and the CXCR4/SDF1 axis (chemokine receptor 4/stromal cell derived factor 1) has been shown for several cancers. However, the role of PGK1 has not been investigated for neuroblastoma, and PGK1 might be a therapeutic ta...

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Bibliographic Details
Main Authors: Helen M Ameis, Astrid Drenckhan, Katharina von Loga, Gabriele Escherich, Katharina Wenke, Jakob R Izbicki, Konrad Reinshagen, Stephanie J Gros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869792?pdf=render