Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation.

The main function attributed to the Rev proteins of immunodeficiency viruses is the shuttling of viral RNAs containing the Rev responsive element (RRE) via the CRM-1 export pathway from the nucleus to the cytoplasm. This restricts expression of structural proteins to the late phase of the lentiviral...

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Bibliographic Details
Main Authors: Sabine Brandt, Maik Blissenbach, Bastian Grewe, Rebecca Konietzny, Thomas Grunwald, Klaus Uberla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1851978?pdf=render