Shiga Toxins Induce Apoptosis and ER Stress in Human Retinal Pigment Epithelial Cells

Shiga Toxins Induce Apoptosis and ER Stress in Human Retinal Pigment Epithelial Cells

Shiga toxins (Stxs) produced by Shiga toxin-producing bacteria Shigella dysenteriae serotype 1 and select serotypes of Escherichia coli are the most potent known virulence factors in the pathogenesis of hemorrhagic colitis progressing to potentially fatal systemic complications such as acute renal f...

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Bibliographic Details
Main Authors: Jun-Young Park, Yu-Jin Jeong, Sung-Kyun Park, Sung-Jin Yoon, Song Choi, Dae Gwin Jeong, Su Wol Chung, Byung Joo Lee, Jeong Hun Kim, Vernon L. Tesh, Moo-Seung Lee, Young-Jun Park
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
Shiga toxins
Shiga toxin type 1 and 2
Shiga toxin-producing Escherichia coli
hemolytic uremic syndrome
signaling pathways
apoptosis
retinal pigment epithelial cells
Online Access:https://www.mdpi.com/2072-6651/9/10/319

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https://www.mdpi.com/2072-6651/9/10/319

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