Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis

Abstract Background Plasmodium falciparum infections with slow parasite clearance following artemisinin-based therapies are widespread in the Greater Mekong Subregion. A molecular marker of the slow clearance phenotype has been identified: single genetic changes within the propeller region of the Ke...

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Bibliographic Details
Main Author: WWARN K13 Genotype-Phenotype Study Group
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Medicine
Online Access:http://link.springer.com/article/10.1186/s12916-018-1207-3