Purinergic Calcium Signals in Tumor-Derived Endothelium

Purinergic Calcium Signals in Tumor-Derived Endothelium

Tumor microenvironment is particularly enriched with extracellular ATP (eATP), but conflicting evidence has been provided on its functional effects on tumor growth and vascular remodeling. We have previously shown that high eATP concentrations exert a strong anti-migratory, antiangiogenic and normal...

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Bibliographic Details
Main Authors: Giorgia Scarpellino, Tullio Genova, Daniele Avanzato, Michela Bernardini, Serena Bianco, Sara Petrillo, Emanuela Tolosano, Joana Rita de Almeida Vieira, Benedetta Bussolati, Alessandra Fiorio Pla, Luca Munaron
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
tumor-derived endothelial cells
endothelium
purinergic signaling
purinergic receptors
ion channels
calcium signaling
tumor angiogenesis
migration
Online Access:https://www.mdpi.com/2072-6694/11/6/766

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https://www.mdpi.com/2072-6694/11/6/766

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