Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors As a First Step in Protection from Xenobiotics

This mini-review examines the crucial importance of transcription factors as a first line of defense in the detoxication of xenobiotics. Key transcription factors that recognize xenobiotics or xenobiotic-induced stress such as reactive oxygen species (ROS), include AhR, PXR, CAR, MTF, Nrf2, NF-κB, a...

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Bibliographic Details
Main Author: William S. Baldwin
Format: Article
Language:English
Published: KenzPub 2019-11-01
Series:Nuclear Receptor Research
Subjects:
Online Access:https://www.kenzpub.com/journals/nurr/2019/101447/