Improving eukaryotic genome annotation using single molecule mRNA sequencing

Improving eukaryotic genome annotation using single molecule mRNA sequencing

Abstract Background The advantages of Pacific Biosciences (PacBio) single-molecule real-time (SMRT) technology include long reads, low systematic bias, and high consensus read accuracy. Here we use these attributes to improve on the genome annotation of the parasitic hookworm Ancylostoma ceylanicum...

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Bibliographic Details
Main Authors: Vincent Magrini, Xin Gao, Bruce A. Rosa, Sean McGrath, Xu Zhang, Kymberlie Hallsworth-Pepin, John Martin, John Hawdon, Richard K. Wilson, Makedonka Mitreva
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Genomics
Subjects:
Genome annotation improvement
Pacific bioscience mRNA sequencing
Ancylostoma ceylanicum
Hookworm
Gene loci
Online Access:http://link.springer.com/article/10.1186/s12864-018-4555-7

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http://link.springer.com/article/10.1186/s12864-018-4555-7

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