Depletion of ATP and glucose in advanced human atherosclerotic plaques.

Depletion of ATP and glucose in advanced human atherosclerotic plaques.

OBJECTIVE:Severe hypoxia develops close to the necrotic core of advanced human atherosclerotic plaques, but the energy metabolic consequences of this hypoxia are not known. In animal models, plaque hypoxia is also associated with depletion of glucose and ATP. ATP depletion may impair healing of plaq...

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Bibliographic Details
Main Authors: Matias Ekstrand, Emma Widell, Anna Hammar, Levent M Akyürek, Martin Johansson, Björn Fagerberg, Göran Bergström, Malin C Levin, Per Fogelstrand, Jan Borén, Max Levin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5453577?pdf=render

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http://europepmc.org/articles/PMC5453577?pdf=render

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