Hyperosmolarity impedes the cross-priming competence of dendritic cells in a TRIF-dependent manner

Abstract Tissue osmolarity varies among different organs and can be considerably increased under pathologic conditions. Hyperosmolarity has been associated with altered stimulatory properties of immune cells, especially macrophages and dendritic cells. We have recently reported that dendritic cells...

Full description

Bibliographic Details
Main Authors: Zoran V. Popovic, Maria Embgenbroich, Federica Chessa, Viola Nordström, Mahnaz Bonrouhi, Thomas Hielscher, Norbert Gretz, Shijun Wang, Daniel Mathow, Thomas Quast, Jan-Gero Schloetel, Waldemar Kolanus, Sven Burgdorf, Hermann-Josef Gröne
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00434-y