Ginkgolide B Maintains Calcium Homeostasis in Hypoxic Hippocampal Neurons by Inhibiting Calcium Influx and Intracellular Calcium Release

Ginkgolide B Maintains Calcium Homeostasis in Hypoxic Hippocampal Neurons by Inhibiting Calcium Influx and Intracellular Calcium Release

Ginkgolide B (GB), a terpene lactone and active ingredient of Ginkgo biloba, shows protective effects in neuronal cells subjected to hypoxia. We investigated whether GB might protect neurons from hypoxic injury through regulation of neuronal Ca2+ homeostasis. Primary hippocampal neurons subjected to...

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Bibliographic Details
Main Authors: Li Wang, Quan Lei, Shuai Zhao, WenJuan Xu, Wei Dong, JiHua Ran, QingHai Shi, JianFeng Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ginkgolide B
hypoxia
cytoplasmic calcium
neuron
homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.627846/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2020.627846/full

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