Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia.

Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia.

<h4>Introduction</h4>Classic ataxia telangiectasia (A-T) is an autosomal recessive disease characterized by early onset ataxia, immune deficiency, sino-pulmonary disease, lymphoid/solid malignancies and telangiectasias. Prior studies have suggested that chronic inflammation and premature...

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Bibliographic Details
Main Authors: Sharon A McGrath-Morrow, Roland Ndeh, Joseph M Collaco, Cynthia Rothblum-Oviatt, Jennifer Wright, Michael A O'Reilly, Benjamin D Singer, Howard M Lederman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209496

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https://doi.org/10.1371/journal.pone.0209496

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