DNA Damage Response in Hematopoietic Stem Cell Ageing

Maintenance of tissue-specific stem cells is vital for organ homeostasis and organismal longevity. Hematopoietic stem cells (HSCs) are the most primitive cell type in the hematopoietic system. They divide asymmetrically and give rise to daughter cells with HSC identity (self-renewal) and progenitor...

Full description

Bibliographic Details
Main Authors: Tangliang Li, Zhong-Wei Zhou, Zhenyu Ju, Zhao-Qi Wang
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
P53
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022916300699