Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis.

Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis.

The TOCA family of F-BAR-containing proteins bind to and remodel lipid bilayers via their conserved F-BAR domains, and regulate actin dynamics via their N-Wasp binding SH3 domains. Thus, these proteins are predicted to play a pivotal role in coordinating membrane traffic with actin dynamics during c...

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Bibliographic Details
Main Authors: Chiara Giuliani, Flavia Troglio, Zhiyong Bai, Falshruti B Patel, Adriana Zucconi, Maria Grazia Malabarba, Andrea Disanza, Theresia B Stradal, Giuseppe Cassata, Stefano Confalonieri, Jeffrey D Hardin, Martha C Soto, Barth D Grant, Giorgio Scita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2744924?pdf=render

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http://europepmc.org/articles/PMC2744924?pdf=render

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