KML001 displays vascular disrupting properties and irinotecan combined antitumor activities in a murine tumor model.

KML001 displays vascular disrupting properties and irinotecan combined antitumor activities in a murine tumor model.

KML001 is sodium metaarsenite, and has shown cytotoxic activity in human tumor cell lines. The anti-cancer mechanism of KML001 involves cancer cell destruction due to DNA damage at the telomeres of cancer cell chromosomes. In this study, we assessed the vascular disrupting properties of KML001 and i...

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Bibliographic Details
Main Authors: Chang Hoon Moon, Seung Ju Lee, Ho Yong Lee, Jong Cheol Lee, Heejeong Cha, Wha Ja Cho, Jeong Woo Park, Hyun Jin Park, Jin Seo, Young Han Lee, Ho-Taek Song, Young Joo Min
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326531/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326531/?tool=EBI

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