Membrane Charge Directs the Outcome of F-BAR Domain Lipid Binding and Autoregulation

Membrane Charge Directs the Outcome of F-BAR Domain Lipid Binding and Autoregulation

F-BAR domain proteins regulate and sense membrane curvature by interacting with negatively charged phospholipids and assembling into higher-order scaffolds. However, regulatory mechanisms controlling these interactions are poorly understood. Here, we show that Drosophila Nervous Wreck (Nwk) is autor...

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Bibliographic Details
Main Authors: Charlotte F. Kelley, Emily M. Messelaar, Tania L. Eskin, Shiyu Wang, Kangkang Song, Kalanit Vishnia, Agata N. Becalska, Oleg Shupliakov, Michael F. Hagan, Dganit Danino, Olga S. Sokolova, Daniela Nicastro, Avital A. Rodal
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Subjects:
Drosophila
Nwk
F-BAR domain
SH3 domain
membrane
PI(4,5)P2
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715013595

Internet

http://www.sciencedirect.com/science/article/pii/S2211124715013595

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