DETERMINANT VALUE OF THE CYTOGENETIC AND MOLECULAR IMATINIB THERAPEUTIC RESPONSE IN CHRONIC MYELOID LEUKEMIA

DETERMINANT VALUE OF THE CYTOGENETIC AND MOLECULAR IMATINIB THERAPEUTIC RESPONSE IN CHRONIC MYELOID LEUKEMIA

The hallmark of chronic myeloid leukemia is the existence of the cytogenetic evidence of the Phyladelphia chromosome (reciprocal translocation between chromosome 9 and 22, and is specifically designated t(9;22)(q34;q11). The result of the translocation is the oncogenic BCR-ABL gene fusion, located o...

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Bibliographic Details
Main Authors: Angela Dascalescu, Cristina Burcoveanu, Iuliu Ivanov, Georgiana Grigore, Mihaela Zlei, Cornel Bujoran, Daniela Jitaru, Gabriela Dorohoi, Ion Antohe, Catalin Danaila
Format: Article
Language:English
Published: "Alexandru Ioan Cuza" University of Iași 2013-12-01
Series:Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
Online Access:http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/1076

Internet

http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/1076

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