Revisiting chemoaffinity theory: Chemotactic implementation of topographic axonal projection.

Neural circuits are wired by chemotactic migration of growth cones guided by extracellular guidance cue gradients. How growth cone chemotaxis builds the macroscopic structure of the neural circuit is a fundamental question in neuroscience. I addressed this issue in the case of the ordered axonal pro...

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Bibliographic Details
Main Author: Honda Naoki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5562328?pdf=render