Small mitochondrial-targeted RNAs modulate endogenous mitochondrial protein expression in vivo

Endogenous mitochondrial genes encode critical oxidative phosphorylation components and their mutation results in a set of disorders known collectively as mitochondrial encephalomyopathies. There is intensive interest in modulating mitochondrial function as organelle dysfunction has been associated...

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Bibliographic Details
Main Authors: Atif Towheed, Desiree M. Markantone, Aaron T. Crain, Alicia M. Celotto, Michael J. Palladino
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001065