Small mitochondrial-targeted RNAs modulate endogenous mitochondrial protein expression in vivo
Endogenous mitochondrial genes encode critical oxidative phosphorylation components and their mutation results in a set of disorders known collectively as mitochondrial encephalomyopathies. There is intensive interest in modulating mitochondrial function as organelle dysfunction has been associated...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-09-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996114001065 |