Development of an Optimized Protocol for NMR Metabolomics Studies of Human Colon Cancer Cell Lines and First Insight from Testing of the Protocol Using DNA G-Quadruplex Ligands as Novel Anti-Cancer Drugs

Development of an Optimized Protocol for NMR Metabolomics Studies of Human Colon Cancer Cell Lines and First Insight from Testing of the Protocol Using DNA G-Quadruplex Ligands as Novel Anti-Cancer Drugs

The study of cell lines by nuclear magnetic resonance (NMR) spectroscopy metabolomics represents a powerful tool to understand how the local metabolism and biochemical pathways are influenced by external or internal stimuli. In particular, the use of adherent mammalian cells is emerging in the metab...

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Bibliographic Details
Main Authors: Ilaria Lauri, Francesco Savorani, Nunzia Iaccarino, Pasquale Zizza, Luigi Michele Pavone, Ettore Novellino, Søren Balling Engelsen, Antonio Randazzo
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Metabolites
Subjects:
cell metabolomics
colon cancer
NMR spectroscopy
Multivariate statistical analysis
G-quadruplex ligands
Online Access:http://www.mdpi.com/2218-1989/6/1/4

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http://www.mdpi.com/2218-1989/6/1/4

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