Efficiency and effectiveness of the use of an acenocoumarol pharmacogenetic dosing algorithm versus usual care in patients with venous thromboembolic disease initiating oral anticoagulation: study protocol for a randomized controlled trial

<p>Abstract</p> <p>Background</p> <p>Hemorrhagic events are frequent in patients on treatment with antivitamin-K oral anticoagulants due to their narrow therapeutic margin. Studies performed with acenocoumarol have shown the relationship between demographic, clinical an...

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Main Authors: Carcas Antonio J, Borobia Alberto M, Velasco Marta, Abad-Santos Francisco, Díaz Manuel Quintana, Fernández-Capitán Carmen, Ruiz-Giménez Nuria, Madridano Olga, Sillero Pilar Llamas
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Trials
Subjects:
Online Access:http://www.trialsjournal.com/content/13/1/239