Sweet and Sour Ehrlichia: Glycoproteomics and Phosphoproteomics Reveal New Players in Ehrlichia ruminantium Physiology and Pathogenesis

Sweet and Sour Ehrlichia: Glycoproteomics and Phosphoproteomics Reveal New Players in Ehrlichia ruminantium Physiology and Pathogenesis

Unraveling which proteins and post-translational modifications (PTMs) affect bacterial pathogenesis and physiology in diverse environments is a tough challenge. Herein, we used mass spectrometry-based assays to study protein phosphorylation and glycosylation in Ehrlichia ruminantium Gardel virulent...

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Bibliographic Details
Main Authors: Isabel Marcelino, Núria Colomé-Calls, Philippe Holzmuller, Frédérique Lisacek, Yann Reynaud, Francesc Canals, Nathalie Vachiéry
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
Ehrlichia ruminantium
phosphoproteins
S/T/Y phosphorylation
N-glycoproteins
O-GlcNAcylated proteins
bacteria physiology
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00450/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.00450/full

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