Enhancement of antitumor immunity using a DNA-based replicon vaccine derived from Semliki Forest virus.

Enhancement of antitumor immunity using a DNA-based replicon vaccine derived from Semliki Forest virus.

A DNA-based replicon vaccine derived from Semliki Forest virus, PSVK-shFcG-GM/B7.1 (Fig. 1a) was designed for tumor immunotherapy as previously constructed. The expression of the fusion tumor antigen (survivin and hCGβ-CTP37) and adjuvant molecular protein (Granulocyte-Macrophage Colony-Stimulating...

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Bibliographic Details
Main Authors: Liang Zhang, Yue Wang, Yi Xiao, Yu Wang, JinKai Dong, Kun Gao, Yan Gao, Xi Wang, Wei Zhang, Yuanji Xu, JinQi Yan, JiYun Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946523?pdf=render

Internet

http://europepmc.org/articles/PMC3946523?pdf=render

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