A Neutralization Assay Based on Pseudo-Typed Lentivirus with SARS CoV-2 Spike Protein in ACE2-Expressing CRFK Cells

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly pathogenic zoonotic virus that spreads rapidly. In this work, we improve the hitherto existing neutralization assay system to assess SARS-CoV-2 inhibitors using a pseudo-typed lentivirus coated with the SARS-CoV-2 spike protein...

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Bibliographic Details
Main Authors: Yalçın Pısıl ⊃⊃, Hisatoshi Shida, Tomoyuki Miura
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pathogens
Subjects:
HIV
Online Access:https://www.mdpi.com/2076-0817/10/2/153