Extracellular Glutamate in the Nucleus Accumbens Is Nanomolar in Both Synaptic and Non-synaptic Compartments

In the CNS, glutamate is both phasically and tonically released into the extracellular space and must be removed by excitatory amino acid transporters (EAATs) to prevent excitotoxic accumulation. There remains uncertainty, however, regarding the functional steady-state concentration, with estimates...

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Bibliographic Details
Main Authors: Delia N. Chiu, Craig E. Jahr
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717302450