Molecular mechanisms of the glucocorticoid receptor in steroid therapy – lessons from transgenic mice

Glucocorticoids (GCs) are potent anti-inflammatory agents that are used to treat chronic inflammatory diseases, allergic conditions, and some cancers. However, their therapeutic effects are hampered by severe side effects, such as muscle weakness, insulin resistance, fat redistribution, and osteopor...

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Bibliographic Details
Main Authors: Hübner Sabine, Tuckermann Jan
Format: Article
Language:English
Published: De Gruyter 2012-06-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2011-0033