Molecular mechanisms of the glucocorticoid receptor in steroid therapy – lessons from transgenic mice
Glucocorticoids (GCs) are potent anti-inflammatory agents that are used to treat chronic inflammatory diseases, allergic conditions, and some cancers. However, their therapeutic effects are hampered by severe side effects, such as muscle weakness, insulin resistance, fat redistribution, and osteopor...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2012-06-01
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Series: | Biomolecular Concepts |
Subjects: | |
Online Access: | https://doi.org/10.1515/bmc-2011-0033 |