Synthesis, Characterization and Antioxidant Properties of a New Lipophilic Derivative of Edaravone

As part of a program aimed to obtain antioxidants able to interact with cell membrane, edaravone (EdV, 3-methyl-1-phenyl-2-pyrazolin-5-one), a well-known free radical scavenger, has been modified by alkylation at its allylic position (4) with a C-18 hydrocarbon chain, and the increased lipophilicity...

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Bibliographic Details
Main Authors: Cristina Minnelli, Emiliano Laudadio, Roberta Galeazzi, Dario Rusciano, Tatiana Armeni, Pierluigi Stipa, Mattia Cantarini, Giovanna Mobbili
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/8/8/258