Persistent activation of central amygdala CRF neurons helps drive the immediate fear extinction deficit

Learned conditioned fear associations can be weakened (extinction learning), but extinction is less effective if performed too soon after the original fear conditioning. Here, the authors show that persistent activation of CRF-expressing neurons in the central amygdala is involved in the early fear...

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Bibliographic Details
Main Authors: Yong S. Jo, Vijay Mohan K. Namboodiri, Garret D. Stuber, Larry S. Zweifel
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14393-y