PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway

Abstract Glioblastoma multiforme (GBM) is the most aggressive brain tumor, with a 5-year survival ratio <5%. Invasive growth is a major determinant of the poor prognosis in GBM. In this study, we demonstrate that high expression of PPFIA binding protein 1 (PPFIBP1) correlates with remarkable inva...

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Bibliographic Details
Main Authors: Caihua Dong, Xinying Li, Jiao Yang, Detian Yuan, Yuanshuai Zhou, Yina Zhang, Guohua Shi, Ruobing Zhang, Jianping Liu, Peng Fu, Minxuan Sun
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04107-7