PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway
Abstract Glioblastoma multiforme (GBM) is the most aggressive brain tumor, with a 5-year survival ratio <5%. Invasive growth is a major determinant of the poor prognosis in GBM. In this study, we demonstrate that high expression of PPFIA binding protein 1 (PPFIBP1) correlates with remarkable inva...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04107-7 |