Application of an Online-Biomass Sensor in an Optical Multisensory Platform Prototype for Growth Monitoring of Biotechnical Relevant Microorganism and Cell Lines in Single-Use Shake Flasks

Application of an Online-Biomass Sensor in an Optical Multisensory Platform Prototype for Growth Monitoring of Biotechnical Relevant Microorganism and Cell Lines in Single-Use Shake Flasks

In the context of this work we evaluated a multisensory, noninvasive prototype platform for shake flask cultivations by monitoring three basic parameters (pH, pO2 and biomass). The focus lies on the evaluation of the biomass sensor based on backward light scattering. The application spectrum was exp...

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Bibliographic Details
Main Authors: Christian Ude, Jörg Schmidt-Hager, Michael Findeis, Gernot Thomas John, Thomas Scheper, Sascha Beutel
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Sensors
Subjects:
biomass sensor
light scattering
optical density
process monitoring
shake flask
Online Access:http://www.mdpi.com/1424-8220/14/9/17390

Internet

http://www.mdpi.com/1424-8220/14/9/17390

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