Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice.

Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice.

Missense mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are linked to autosomal dominant forms of Parkinson's disease (PD). In order to get insights into the physiological role of Lrrk2, we examined the distribution of Lrrk2 mRNA and different splice variants in the developing murin...

Full description

Bibliographic Details
Main Authors: Florian Giesert, Andreas Hofmann, Alexander Bürger, Julia Zerle, Karina Kloos, Ulrich Hafen, Luise Ernst, Jingzhong Zhang, Daniela Maria Vogt-Weisenhorn, Wolfgang Wurst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3651128?pdf=render

Internet

http://europepmc.org/articles/PMC3651128?pdf=render

Similar Items