Hnf-1β transcription factor is an early hif-1α-independent marker of epithelial hypoxia and controls renal repair.

Hnf-1β transcription factor is an early hif-1α-independent marker of epithelial hypoxia and controls renal repair.

Epithelial repair following acute kidney injury (AKI) requires epithelial-mesenchyme-epithelial cycling associated with transient re-expression of genes normally expressed during kidney development as well as activation of growth factors and cytokine-induced signaling. In normal kidney, the Hnf-1β t...

Full description

Bibliographic Details
Main Authors: Stanislas Faguer, Nicolas Mayeur, Audrey Casemayou, Anne-Laure Pageaud, Claire Courtellemont, Claire Cartery, Gilbert J Fournie, Joost P Schanstra, Ivan Tack, Jean-Loup Bascands, Dominique Chauveau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660442?pdf=render

Internet

http://europepmc.org/articles/PMC3660442?pdf=render

Similar Items