High PD-1 expression on regulatory and effector T-cells in lung cancer draining lymph nodes

The treatment of advanced nonsmall cell lung cancer (NSCLC) with PD-1/PD-L1 immune checkpoint inhibitors has improved clinical outcome for a proportion of patients. The current challenge is to find better biomarkers than PD-L1 immunohistochemistry (IHC) that will identify patients likely to benefit...

Full description

Bibliographic Details
Main Authors: Rieneke van de Ven, Anna-Larissa N. Niemeijer, Anita G.M. Stam, Sayed M.S. Hashemi, Christian G. Slockers, Johannes M. Daniels, Erik Thunnissen, Egbert F. Smit, Tanja D. de Gruijl, Adrianus J. de Langen
Format: Article
Language:English
Published: European Respiratory Society 2017-05-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/3/2/00110-2016.full