Deterministic column subset selection for single-cell RNA-Seq.

Analysis of single-cell RNA sequencing (scRNA-Seq) data often involves filtering out uninteresting or poorly measured genes and dimensionality reduction to reduce noise and simplify data visualization. However, techniques such as principal components analysis (PCA) fail to preserve non-negativity an...

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Bibliographic Details
Main Authors: Shannon R McCurdy, Vasilis Ntranos, Lior Pachter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210571

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