Defining HIV and SIV Reservoirs in Lymphoid Tissues

Defining HIV and SIV Reservoirs in Lymphoid Tissues

A primary obstacle to an HIV-1 cure is long-lived viral reservoirs, which must be eliminated or greatly reduced. Cure strategies have largely focused on monitoring changes in T cell reservoirs in peripheral blood (PB), even though the lymphoid tissues (LT) are primary sites for viral persistence. To...

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Bibliographic Details
Main Authors: Claire Deleage, Stephen W. Wietgrefe, Gregory Del Prete, David R. Morcock, Xing-Pei Hao, Michael Piatak, Jr., Julian Bess, Jodi L. Anderson, Katherine Perkey, Cavan Reilly, Joseph M. McCune, Ashley T. Haase, Jeffrey D. Lifson, Timothy W. Schacker, Jacob D. Estes
Format: Article
Language:English
Published: Case Western Reserve University 2016-06-01
Series:Pathogens and Immunity
Subjects:
HIV
SIV, Reservoir
Follicular Dendritic Cells
B cell follicles
In situ hybridization
RNAscope
DNAscope
Online Access:https://paijournal.com/index.php/paijournal/article/view/100

Internet

https://paijournal.com/index.php/paijournal/article/view/100

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