<i>IsoSearch</i>: An Untargeted and Unbiased Metabolite and Lipid Isotopomer Tracing Strategy from HR-LC-MS/MS Datasets

<i>IsoSearch</i>: An Untargeted and Unbiased Metabolite and Lipid Isotopomer Tracing Strategy from HR-LC-MS/MS Datasets

Stable isotopic tracer analysis is a technique used to determine carbon or nitrogen atom incorporation into biological systems. A number of mass spectrometry based approaches have been developed for this purpose, including high-resolution tandem mass spectrometry (HR-LC-MS/MS), selected reaction mon...

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Bibliographic Details
Main Authors: He Huang, Min Yuan, Phillip Seitzer, Susan Ludwigsen, John M. Asara
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Methods and Protocols
Subjects:
stable isotope labeling
flux
isotopic tracer analysis
polarity switching
high resolution
liquid chromatography
Online Access:https://www.mdpi.com/2409-9279/3/3/54

Internet

https://www.mdpi.com/2409-9279/3/3/54

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