Perampanel inhibits calcitonin gene-related peptide release from rat brainstem in vitro

Abstract Background Perampanel is a novel antiepileptic drug acting via non-competitive antagonism on glutamatergic AMPA receptors, and the subsequent inhibition of ion calcium influx. Since it was recently postulated that the antagonists of glutamate receptors might play a role in the treatment of...

Full description

Bibliographic Details
Main Authors: Giuseppe Tringali, Diego Currò, Pierluigi Navarra
Format: Article
Language:English
Published: BMC 2018-11-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s10194-018-0940-5